Characteristic | Description |
---|---|
Active Ingredient | Sildenafil Citrate |
Available Dosages | 25 mg, 50 mg, 100 mg |
Form | Oral Tablets |
Prescription Requirement | Yes |
More Information on Fildena |
Fildena, widely recognized in pharmaceutical circles, plays a pivotal role in addressing erectile dysfunction (ED). The action begins as sildenafil citrate, its primary agent, targets specific enzymes within the body. This compound inhibits phosphodiesterase type 5 (PDE5). As a result, the concentration of cyclic guanosine monophosphate (cGMP) rises, promoting enhanced blood flow to the penile region. This process aids men with ED, facilitating normal erectile function. Pharmacokinetically, the absorption rate of Fildena is rapid. Peak plasma levels appear within 30 to 120 minutes post-ingestion. Its half-life is about four hours. Metabolism occurs predominantly in the liver via cytochrome P450 enzymes, and excretion primarily through feces and urine.
Pharmacokinetics
The intricacies of Fildena’s pharmacokinetics offer an insightful glance into its efficacy. Post oral administration, the active ingredient, sildenafil citrate, exhibits prompt absorption. Plasma concentrations peak between one to two hours after dosing. Food can influence this absorption, especially high-fat meals, which delay the onset of action. This is crucial information for patients seeking optimal results from sildenafil 100 mg. The systemic bioavailability stands at approximately 40%. Distribution occurs extensively within the tissues, attributed to its volume of distribution at around 105 liters. The metabolic pathway predominantly involves hepatic enzymes, particularly cytochrome P450 3A4 and 2C9. The drug’s elimination, through both fecal and urinary routes, indicates a terminal half-life of four hours, ensuring the medication’s sustained action without prolonged accumulation in the system.
Other Uses for Fildena
Beyond its primary use for erectile dysfunction, Fildena has potential in addressing other medical conditions. Off-label applications include treatment for pulmonary arterial hypertension (PAH). Sildenafil, the active compound, relaxes blood vessels in the lungs, reducing vascular resistance and pressure. This offers relief for patients experiencing symptoms related to PAH. Furthermore, sildenafil 50 mg demonstrates potential for managing Raynaud’s phenomenon. This condition, characterized by decreased blood flow to extremities, benefits from the vasodilatory effects of Fildena. The drug’s ability to improve vascular function positions it as a versatile agent within clinical settings. However, these uses necessitate thorough consultation with healthcare professionals to ensure safety and efficacy.
Fildena Contraindications
Fildena, though effective, is not suitable for everyone. Key contraindications include patients with a history of hypersensitivity to sildenafil or any component of the tablet. Individuals currently using nitrates or nitric oxide donors, such as isosorbide dinitrate, face significant health risks if combined with sildenafil. The interaction can lead to severe hypotension. Patients with severe cardiovascular disorders, including recent myocardial infarction or stroke, are advised against using Fildena 100 mg. Retinal disorders, such as retinitis pigmentosa, also contraindicate its use due to potential exacerbation. Moreover, it is unsuitable for patients with severe hepatic impairment or end-stage renal disease, where the drug’s metabolism and excretion may be compromised.
Fildena Storage
Proper storage of Fildena ensures its efficacy and longevity. Tablets should remain in their original packaging until use. Store in a cool, dry place, away from direct sunlight. The recommended storage temperature lies between 15°C and 30°C. Exposure to excessive heat or moisture may degrade the active ingredient, sildenafil citrate. Keeping the medication out of reach of children is crucial. Ensure the container remains tightly closed to prevent contamination or degradation. By adhering to these storage guidelines, the therapeutic integrity of Fildena is maintained, ensuring optimal results upon administration.
Effects of Fildena
The effects of Fildena extend beyond mere physical changes. Its primary role in treating erectile dysfunction restores confidence and enhances quality of life. The drug ensures firm, sustained erections conducive to satisfactory sexual activity. Onset typically occurs within 30 to 60 minutes of ingestion. Duration may extend up to four hours, depending on dosage and individual response. While generally well-tolerated, potential side effects include headache, facial flushing, and dyspepsia. More serious adverse effects, though rare, necessitate immediate medical attention. These include sudden vision loss or hearing impairment. Monitoring and medical oversight ensure Fildena’s benefits outweigh potential risks, offering a reliable option for those with ED.
Where to Buy Fildena Online
Acquiring Fildena online requires careful consideration. Numerous platforms offer sildenafil 100 mg, but verifying their credibility is paramount. Reputable online pharmacies provide assurance of authentic products. A valid prescription is typically necessary, underscoring the importance of prior consultation with healthcare providers. Comparisons of pricing, shipping options, and customer reviews aid in selecting a trustworthy source. Secure payment methods further ensure a safe transaction process. By prioritizing verified sellers, patients can confidently purchase Fildena, ensuring their treatment plan remains uninterrupted and effective.
Dosage | Peak Plasma Time | Half-life |
---|---|---|
Fildena 25 mg | 1 hour | 4 hours |
Fildena 50 mg | 1 hour | 4 hours |
Fildena 100 mg | 1 hour | 4 hours |
Fildena remains a cornerstone in the management of erectile dysfunction. Its multifaceted benefits extend to other medical realms, backed by a robust pharmacokinetic profile. While contraindications exist, informed usage mitigates risks, enhancing therapeutic outcomes. Proper storage and procurement from credible sources further solidify its place in modern medicine. For patients seeking a reliable ED treatment, Fildena offers a trusted solution, endorsed by healthcare professionals globally.
Data origin:
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